SCHEMBL9404574

SCHEMBL9404574

[c]1ccc2c(c1)Oc1ccccc1[N]2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALOX5 P09917 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25520 0.80 TRPA1 (0.52) TRPA1CYP1A2CYP2D6ALOX5MAOA
SCHEMBL864104 0.76 AHR (0.38) TRPA1ALOX5MAOAMAOB
SCHEMBL975423 0.71
SCHEMBL2319073 0.69 TRPA1 (0.39) TRPA1CYP1A2CYP2D6ALOX5MAOA
SCHEMBL4603443 0.68
SCHEMBL974277 0.67
SCHEMBL24077 0.67 ALOX5 (0.65) CYP1A2ALOX5MAOA
SCHEMBL195110 0.67 MAOA (0.65) ALOX5MAOAMAOB
SCHEMBL129470 0.67 ATM (0.31) CYP1A2ALOX5MAOAMAOB
SCHEMBL11767356 0.65 TRPA1 (0.52) TRPA1CYP1A2CYP2D6ALOX5MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63317507-A None JP disclosed
EP-1671998-B1 Process to form compound with indolocarbazole moieties XEROX CORP (US) 2013-02-20 EP disclosed
EP-0295084-B1 Novel copolymers and electroactive polymers derived from same NIPPON OIL CO LTD (JP) 1994-09-21 EP disclosed
US-4952667-A Novel copolymers and electroactive polymers derived from same NIPPON OIL COMPANY, LIMITED (JP) 1990-08-28 US disclosed
JP-S63317507-A NOVEL POLYMER AND ELECTRICALLY ACTIVE POLYMER DERIVED THEREFROM NIPPON OIL CO LTD 1988-12-26 JP disclosed
EP-0295084-A2 Novel copolymers and electroactive polymers derived from same NIPPON OIL CO. LTD. (JP) 1988-12-14 EP disclosed