Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 6/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523412 | 0.78 | AHR (0.35) | AHRL3MBTL1RPS6KA3AKR1C3AKR1C2 | |
| SCHEMBL25522217 | 0.74 | RPS6KA3 (0.35) | AHRRPS6KA3CASRKDM4EHSD17B1 | |
| SCHEMBL25521412 | 0.74 | PIK3CD (0.42) | L3MBTL1RPS6KA3KDM4EMPIERN1 | |
| SCHEMBL25523473 | 0.73 | PDE4B (0.34) | HTR1BHTR2BGPR65 | |
| SCHEMBL25523474 | 0.71 | AHR (0.36) | AHRL3MBTL1RPS6KA3AKR1C3AKR1C2 | |
| SCHEMBL25523417 | 0.70 | KDM4E (0.42) | L3MBTL1RPS6KA3KDM4EMPI | |
| SCHEMBL25521555 | 0.69 | ERN1 (0.50) | KDM4EERN1ESR1 | |
| SCHEMBL25523538 | 0.68 | KDM4E (0.55) | KDM4E | |
| SCHEMBL25523415 | 0.66 | ERN1 (0.42) | L3MBTL1AKR1C3AKR1C2KDM4EMPI | |
| SCHEMBL25520068 | 0.65 | RPS6KA3 (0.45) | L3MBTL1RPS6KA3KDM4EHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |