Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520071 | 0.71 | ENPP1 (0.34) | AHRHTR1BHTR2BGPR65HSD17B1 | |
| SCHEMBL25521412 | 0.71 | PIK3CD (0.42) | RPS6KA3KDM4EMPIL3MBTL1 | |
| SCHEMBL25523473 | 0.69 | PDE4B (0.34) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL25523415 | 0.69 | ERN1 (0.42) | MAPTALOX15CASP1HSD17B10AKR1C3 | |
| SCHEMBL25523417 | 0.68 | KDM4E (0.42) | MAPTTDP1THRBRECQLRPS6KA3 | |
| SCHEMBL31555995 | 0.68 | FTO (0.46) | MAPTHPGDALOX15RECQLHSD17B10 | |
| SCHEMBL25523412 | 0.68 | AHR (0.35) | AHRHSD17B1HSD17B2AKR1C3AKR1C2 | |
| SCHEMBL25521555 | 0.66 | ERN1 (0.50) | MAPTALOX15CASP1HSD17B10KDM4E | |
| SCHEMBL725385 | 0.66 | GABRA1 (0.52) | AHRHTR2BMAPTHPGDALOX15 | |
| SCHEMBL12123835 | 0.65 | GABRA1 (0.43) | AHRHTR2BMAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |