Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523412 | 0.95 | AHR (0.35) | RPS6KA3HSD17B1HSD17B2CASRADORA3 | |
| SCHEMBL25521794 | 0.80 | KDM4E (0.39) | HSD17B1HSD17B2KDM4E | |
| SCHEMBL25522344 | 0.77 | CASR (0.36) | HSD17B1HSD17B2CASRGCGR | |
| SCHEMBL25522331 | 0.75 | L3MBTL1 (0.50) | ADORA3ADORA1KDM4E | |
| SCHEMBL25520071 | 0.74 | ENPP1 (0.34) | RPS6KA3HSD17B1HSD17B2CASRKDM4E | |
| SCHEMBL25519641 | 0.72 | GABRA1 (0.44) | RPS6KA3KDM4E | |
| SCHEMBL25522210 | 0.72 | KDM4E (0.42) | HSD17B1HSD17B2KDM4E | |
| SCHEMBL25523414 | 0.70 | KDM4E (0.51) | ADORA3ADORA1KDM4E | |
| SCHEMBL25523538 | 0.70 | KDM4E (0.55) | KDM4E | |
| SCHEMBL31010855 | 0.69 | NPC1 (0.47) | KDM4EAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |