Pipamperone

Pipamperone

SCHEMBL2552074

C=O.NC(=O)C1(N2CCCCC2)CCN(CCCC(=O)c2ccc(F)cc2)CC1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.96
ADRA2A P08913 3/20 0.96
SLC6A4 P31645 3/20 0.96
ADRA1A P35348 3/20 0.96
OPRM1 P35372 3/20 0.96
DRD3 P35462 3/20 0.96
SLC6A3 Q01959 3/20 0.96
KCNH2 Q12809 3/20 0.96
DRD1 P21728 2/20 0.96
HRH3 Q9Y5N1 1/20 0.96
ALDH1A1 P00352 1/20 0.61
DRD2 P14416 7/20 0.58
TSHR P16473 2/20 0.54
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2D6 P10635 2/20 0.53
CHRM1 P11229 2/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53
CHRM3 P20309 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pipamperone SCHEMBL6621425 0.98 HTR1A (1.00) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL2412 0.98 HTR1A (1.00) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL364623 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL14696833 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL4671026 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL647930 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL8764867 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL10533161 0.97 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL8327319 0.96 HTR1A (0.96) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL21357035 0.95 HTR1A (0.94) HTR1AADRA2ASLC6A4ADRA1AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed