Pipamperone

Pipamperone

SCHEMBL647930

N.NC(=O)C1(N2CCCCC2)CCN(CCCC(=O)c2ccc(F)cc2)CC1

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.98
ADRA2A P08913 3/20 0.98
SLC6A4 P31645 3/20 0.98
ADRA1A P35348 3/20 0.98
OPRM1 P35372 3/20 0.98
DRD3 P35462 3/20 0.98
SLC6A3 Q01959 3/20 0.98
KCNH2 Q12809 3/20 0.98
DRD1 P21728 2/20 0.98
HRH3 Q9Y5N1 1/20 0.98
ALDH1A1 P00352 1/20 0.63
DRD2 P14416 7/20 0.60
TSHR P16473 2/20 0.55
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2D6 P10635 2/20 0.54
CHRM1 P11229 2/20 0.54
ADRA2B P18089 2/20 0.54
ADRA2C P18825 2/20 0.54
CHRM3 P20309 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pipamperone SCHEMBL6621425 0.99 HTR1A (1.00) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL2412 0.99 HTR1A (1.00) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL364623 0.98 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL14696833 0.98 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL10533161 0.98 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL4671026 0.98 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL8764867 0.98 HTR1A (0.98) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL8327319 0.97 HTR1A (0.96) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL2552074 0.97 HTR1A (0.96) HTR1AADRA2ASLC6A4ADRA1AOPRM1
Pipamperone SCHEMBL21357035 0.96 HTR1A (0.94) HTR1AADRA2ASLC6A4ADRA1AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010895-A Preparation method of N-hydroxyethyl-3, 4-methylenedioxy aniline 浙江鼎龙科技股份有限公司 2026-05-12 CN claimed
CN-119836121-A Perovskite solar cell based on piperonyl amine additive and preparation method thereof 华北电力大学 2025-04-15 CN claimed
CN-118530208-A Piper-amid compounds and application thereof 扬州大学 2024-08-23 CN claimed
CN-118440109-A Method for synthesizing low-threshold perovskite laser material by taking piperonyl amine as ligand 天津大学 2024-08-06 CN claimed
CN-118203664-A Composition containing at least one natural or synthetic N-alkylamide as active substance and method for producing same 埃利奥诺公司 2024-06-18 CN claimed
CN-118126017-A Preparation method of 3, 4-methylenedioxy-phenylglycolic acid 山东新和成药业有限公司 2024-06-04 CN claimed
CN-117982471-A Application of orange yellow piperamide in preparation of medicine for treating acute kidney injury 安徽医科大学 2024-05-07 CN claimed
CN-115925672-B Preparation method of oxolinic acid intermediate 湖北龙翔药业科技股份有限公司 2024-03-22 CN claimed
CN-114316951-B Cadmium-based two-dimensional hybridization perovskite long afterglow material, and preparation method and application thereof 南京邮电大学 2023-12-22 CN claimed
CN-111868072-B Peptoid compound, preparation method thereof, nano carrier and pharmaceutical composition 京东方科技集团股份有限公司 2023-08-29 CN claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
JP-2000509406-A 2000-07-25 JP claimed
EP-0956031-A1 INHIBITION OF 26S AND 20S PROTEASOME BY INDANONES CV THERAPEUTICS, INC. (US) 1999-11-17 EP claimed
CN-1231612-A Inhibition of 2,3-dihydrogen-indone to 26S and 20S prolease CV THERAPEUTICS INC (US) 1999-10-13 CN claimed
CN-1180073-A Synthetic process of medicinal intermediate piperonyl amine FEED INST OF CHINESE ACADEMY O (CN) 1998-04-29 CN claimed
WO-1998013061-A1 INHIBITION OF 26S AND 20S PROTEASOME BY INDANONES CV THERAPEUTICS, INC. (US) 1998-04-02 WO claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed