Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520064 | 0.80 | TLR8 (0.44) | TLR9TLR8TLR7ALDH1A1KDM4E | |
| SCHEMBL25522057 | 0.80 | TGFBR1 (0.40) | TLR9TLR8TLR7ALDH1A1KDM4E | |
| SCHEMBL25522432 | 0.79 | NR4A2 (0.45) | TLR9TLR8TLR7HSD17B10TGFBR1 | |
| SCHEMBL25521410 | 0.79 | RAF1 (0.41) | TLR9TLR8TLR7PIK3CA | |
| SCHEMBL25523476 | 0.77 | MAPKAPK2 (0.46) | KDR | |
| SCHEMBL25521665 | 0.76 | RPS6KA3 (0.33) | AHR | |
| SCHEMBL25523543 | 0.76 | TGFBR1 (0.46) | ALDH1A1HPGDHSD17B10TGFBR1EGFR | |
| SCHEMBL8337311 | 0.75 | NPC1 (0.52) | TGFBR1HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL21508010 | 0.75 | OGA (0.41) | TLR9TLR8TLR7ALDH1A1KDM4E | |
| SCHEMBL25523539 | 0.74 | CYP1A2 (0.42) | TLR9TLR8TLR7KDM4EPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |