Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522336 | 0.91 | TLR8 (0.40) | TLR8RETRIPK1RIPK3CCR1 | |
| SCHEMBL25522432 | 0.84 | NR4A2 (0.45) | TLR8TGFBR1RIPK2EGFRALK | |
| SCHEMBL25524005 | 0.82 | TLR8 (0.41) | TLR8RETRIPK1RIPK3CCR1 | |
| SCHEMBL25521679 | 0.80 | TLR9 (0.41) | TLR8TGFBR1EGFRTLR9TLR7 | |
| SCHEMBL25522342 | 0.77 | NR4A2 (0.40) | TLR8TGFBR1RIPK2EGFRTLR9 | |
| SCHEMBL25521410 | 0.76 | RAF1 (0.41) | TLR8TLR9TLR7MAPKAPK2 | |
| SCHEMBL25523476 | 0.74 | MAPKAPK2 (0.46) | RETRIPK2MAPKAPK2 | |
| SCHEMBL30726157 | 0.73 | INPPL1 (0.35) | TLR8 | |
| SCHEMBL25523543 | 0.73 | TGFBR1 (0.46) | TGFBR1EGFRALDH1A1HPGDMAPK1 | |
| SCHEMBL25519630 | 0.72 | AURKA (0.49) | TLR8RETCCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |