Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522342 | 0.91 | NR4A2 (0.40) | NR4A2SOS2NCF1TLR8CYP3A4 | |
| SCHEMBL25520064 | 0.84 | TLR8 (0.44) | TLR8HSD17B10EGFRTLR7TLR9 | |
| SCHEMBL25521679 | 0.79 | TLR9 (0.41) | TLR8HSD17B10EGFRPIK3CDABL1 | |
| SCHEMBL25522336 | 0.76 | TLR8 (0.40) | TLR8EGFRRIPK2TGFBR1 | |
| SCHEMBL25521410 | 0.75 | RAF1 (0.41) | TLR8PIK3CATLR7TLR9 | |
| SCHEMBL23430687 | 0.73 | NR4A2 (0.56) | NR4A2SOS2NCF1ALKSYK | |
| SCHEMBL25523476 | 0.73 | MAPKAPK2 (0.46) | KDRRIPK2 | |
| SCHEMBL15138972 | 0.72 | NCF1 (0.58) | NR4A2SOS2NCF1ALOX15HSD17B10 | |
| SCHEMBL12545963 | 0.72 | NR4A2 (0.56) | NR4A2SOS2NCF1ALOX15HSD17B10 | |
| SCHEMBL25521671 | 0.72 | MAP4K4 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |