Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 11/20 | 0.46 |
| ▸ | RAF1 | P04049 | 6/20 | 0.42 |
| ▸ | BRAF | P15056 | 6/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523956 | 0.84 | MAPKAPK2 (0.44) | MAPKAPK2RAF1BRAFRIPK2RET | |
| SCHEMBL25521410 | 0.81 | RAF1 (0.41) | MAPKAPK2RAF1BRAFSLC22A12 | |
| SCHEMBL25523543 | 0.78 | TGFBR1 (0.46) | MAPKAPK2SLC22A12 | |
| SCHEMBL25521679 | 0.77 | TLR9 (0.41) | KDR | |
| SCHEMBL25520064 | 0.74 | TLR8 (0.44) | MAPKAPK2RIPK2RET | |
| SCHEMBL25522432 | 0.73 | NR4A2 (0.45) | RIPK2KDR | |
| SCHEMBL25521671 | 0.73 | MAP4K4 (0.58) | — | |
| SCHEMBL25523411 | 0.69 | AAK1 (0.44) | — | |
| SCHEMBL25053127 | 0.69 | HTR1A (0.70) | MAPKAPK2RIPK2RETKDRMAPK14 | |
| SCHEMBL2621802 | 0.67 | SLC22A12 (0.69) | MAPKAPK2RIPK2HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |