Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522351 | 0.79 | CYP17A1 (0.41) | ERN1KDM4ECYP17A1CYP3A4CYP11B1 | |
| SCHEMBL25522206 | 0.79 | ERN1 (0.45) | ERN1KDM4EMAPTIL1BMET | |
| SCHEMBL25523415 | 0.77 | ERN1 (0.42) | ERN1KDM4EMAPTIL1BMET | |
| SCHEMBL25522347 | 0.73 | KDM4E (0.48) | KDM4ETRPV1L3MBTL1 | |
| SCHEMBL25523901 | 0.71 | ERN1 (0.37) | ERN1KDM4EMAPTIL1BMET | |
| SCHEMBL25522353 | 0.71 | TLR8 (0.38) | ERN1CYP17A1 | |
| SCHEMBL25522344 | 0.68 | CASR (0.36) | — | |
| SCHEMBL14242728 | 0.67 | KDM4E (0.58) | ERN1KDM4EMAPTIL1BMPI | |
| SCHEMBL28150885 | 0.67 | MET (0.45) | KDM4EMAPTMET | |
| SCHEMBL25522349 | 0.66 | ESR1 (0.36) | KDM4EL3MBTL1CYP17A1CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |