Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 5/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523415 | 0.84 | ERN1 (0.42) | ERN1CYP11B2CYP17A1CYP11B1CYP3A4 | |
| SCHEMBL25521916 | 0.84 | ERN1 (0.46) | ERN1AAK1 | |
| SCHEMBL25523903 | 0.82 | KDM4E (0.40) | KDM4EMAPTCOMT | |
| SCHEMBL25522206 | 0.81 | ERN1 (0.45) | ERN1CYP11B2CYP17A1CYP11B1CYP3A4 | |
| SCHEMBL25522046 | 0.81 | CYP11B1 (0.42) | ERN1CYP11B2CYP17A1CYP11B1CYP3A4 | |
| SCHEMBL25521800 | 0.80 | AAK1 (0.47) | AAK1 | |
| SCHEMBL25523899 | 0.78 | AKR1C3 (0.42) | AKR1C3AKR1C2MET | |
| SCHEMBL25523900 | 0.75 | RAF1 (0.39) | — | |
| SCHEMBL25522057 | 0.73 | TGFBR1 (0.40) | CYP3A4KDM4EMAPT | |
| SCHEMBL25524007 | 0.71 | PDGFRB (0.40) | ERN1CYP3A4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |