Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522432 | 0.91 | NR4A2 (0.45) | NR4A2SOS2NCF1TLR8TGFBR1 | |
| SCHEMBL25522336 | 0.86 | TLR8 (0.40) | TLR8TGFBR1EGFRRIPK2AAK1 | |
| SCHEMBL25520064 | 0.77 | TLR8 (0.44) | TLR8TGFBR1EGFRHSD17B10RIPK2 | |
| SCHEMBL25522346 | 0.76 | CYBB (0.34) | NCF1TLR8ALOX5APFEN1TLR9 | |
| SCHEMBL25521410 | 0.76 | RAF1 (0.41) | TLR8PIK3CATLR9TLR7RAF1 | |
| SCHEMBL25522341 | 0.72 | RPS6KA3 (0.36) | TLR8KDRPIK3CAMTORALOX5AP | |
| SCHEMBL25522438 | 0.72 | CYBB (0.34) | NCF1TLR8ALOX5APFEN1TLR9 | |
| SCHEMBL25521679 | 0.71 | TLR9 (0.41) | TLR8TGFBR1EGFRPIK3CDABL1 | |
| SCHEMBL25521665 | 0.71 | RPS6KA3 (0.33) | — | |
| SCHEMBL23430687 | 0.68 | NR4A2 (0.56) | NR4A2SOS2NCF1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |