Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520064 | 0.91 | TLR8 (0.44) | TLR8TGFBR1RETRIPK1RIPK3 | |
| SCHEMBL25522342 | 0.86 | NR4A2 (0.40) | TLR8TGFBR1RIPK2EGFRRAF1 | |
| SCHEMBL27033369 | 0.80 | SYK (0.37) | TGFBR1CSF1RRAF1BRAFAAK1 | |
| SCHEMBL27033254 | 0.80 | INPPL1 (0.35) | TLR8CSF1RRAF1BRAFAAK1 | |
| SCHEMBL30726157 | 0.80 | INPPL1 (0.35) | TLR8CSF1RRAF1BRAFAAK1 | |
| SCHEMBL27033333 | 0.78 | SYK (0.33) | TLR8CSF1RAAK1 | |
| SCHEMBL25522353 | 0.78 | TLR8 (0.38) | TLR8TGFBR1ERN1RETRIPK1 | |
| SCHEMBL25524005 | 0.77 | TLR8 (0.41) | TLR8TGFBR1RETRIPK1RIPK3 | |
| SCHEMBL25521410 | 0.76 | RAF1 (0.41) | TLR8RAF1BRAF | |
| SCHEMBL25522432 | 0.76 | NR4A2 (0.45) | TLR8TGFBR1RIPK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |