Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475607 | 0.83 | LRRK2 (0.52) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL22518612 | 0.83 | LRRK2 (0.52) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL30475605 | 0.80 | LRRK2 (0.38) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL30955629 | 0.80 | LRRK2 (0.38) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL22518608 | 0.80 | LRRK2 (0.38) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL23725218 | 0.76 | ALDH1A1 (0.40) | LRRK2CDK1PDE2AYTHDC1SMN1; SMN2 | |
| SCHEMBL22518631 | 0.76 | LRRK2 (0.59) | LRRK2CDK1PDE2ASMN1; SMN2 | |
| SCHEMBL4191097 | 0.74 | — | — | |
| SCHEMBL12889638 | 0.72 | MAT2A (0.34) | LRRK2 | |
| SCHEMBL30503533 | 0.72 | MAT2A (0.34) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | LRRK2 729/4885CDK1 192/4885PDE2A 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.