Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.62 |
| ▸ | TST | Q16762 | 1/20 | 0.62 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergocalciferol SCHEMBL4000117 | 0.84 | ALDH1A1 (0.78) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL9051068 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL9049815 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL15081680 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL322423 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL24066841 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL2695315 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL15081682 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL21433257 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 | |
| Doxercalciferol SCHEMBL9980581 | 0.82 | VDR (1.00) | VDRLMNAADRA1AARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023681-A1 | STABILIZED DOXERCALCIFEROL AND PROCESS FOR MANUFACTURING THE SAME | ALPHORA RESEARCH INC. (CA) | 2013-01-24 | — | — | US | disclosed |
| WO-2011120162-A1 | STABILIZED DOXERCALCIFEROL AND PROCESS FOR MANUFACTURING THE SAME | ALPHORA RESEARCH INC. (CA) | 2011-10-06 | — | — | WO | disclosed |