Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ME2 | P23368 | 2/20 | 0.38 |
| ▸ | ME1 | P48163 | 2/20 | 0.38 |
| ▸ | ME3 | Q16798 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248916 | 1.00 | PANK3 (0.50) | PANK3AKR1C3MMP1MMP2MMP8 | |
| SCHEMBL2241911 | 0.89 | MMP1 (0.56) | PANK3AKR1C3MMP1MMP2MMP8 | |
| SCHEMBL2552328 | 0.89 | MMP1 (0.56) | PANK3AKR1C3MMP1MMP2MMP8 | |
| SCHEMBL2549668 | 0.88 | PANK3 (0.52) | PANK3PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL2247529 | 0.88 | PANK3 (0.52) | PANK3PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL2252745 | 0.82 | ALDH1A1 (0.58) | PANK3HPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2249019 | 0.82 | ALDH1A1 (0.58) | PANK3HPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2247600 | 0.80 | MMP1 (0.55) | PANK3MMP1MMP2MMP8ME2 | |
| SCHEMBL2552096 | 0.80 | MMP1 (0.55) | PANK3MMP1MMP2MMP8ME2 | |
| SCHEMBL2545875 | 0.77 | MAPK1 (0.47) | MMP1MMP2MMP8SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | PANK3 3763/4885AKR1C3 645/4885MMP1 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.