Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522331 | 0.96 | L3MBTL1 (0.50) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25521795 | 0.84 | KDM4E (0.48) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25521549 | 0.81 | DYRK1A (0.50) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25521665 | 0.78 | RPS6KA3 (0.33) | ADORA1 | |
| SCHEMBL25523475 | 0.78 | KDM4E (0.44) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25522347 | 0.77 | KDM4E (0.48) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25523417 | 0.77 | KDM4E (0.42) | KDM4EL3MBTL1NPC1COMTMPI | |
| SCHEMBL25521674 | 0.77 | PDE4D (0.46) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25521416 | 0.76 | AKR1C3 (0.45) | KDM4ERAB9ANPC1RIPK1MET | |
| SCHEMBL28275870 | 0.74 | L3MBTL1 (0.66) | KDM4EL3MBTL1RAB9ANPC1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |