Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 15/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521416 | 0.84 | AKR1C3 (0.45) | AKR1C3AKR1C2METNPC1MEN1 | |
| SCHEMBL25524004 | 0.83 | PDGFRB (0.51) | NPC1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL25522051 | 0.80 | RPS6KA3 (0.42) | AKR1C3AKR1C2 | |
| SCHEMBL25523901 | 0.78 | ERN1 (0.37) | AKR1C3AKR1C2MET | |
| SCHEMBL25521795 | 0.77 | KDM4E (0.48) | METNPC1 | |
| SCHEMBL25521916 | 0.76 | ERN1 (0.46) | KDR | |
| SCHEMBL25523955 | 0.75 | KDM4E (0.43) | NPC1 | |
| SCHEMBL25523903 | 0.75 | KDM4E (0.40) | NPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL25524048 | 0.74 | IRAK4 (0.33) | AKR1C3AKR1C2KDR | |
| SCHEMBL25524104 | 0.73 | PDGFRB (0.51) | AKR1C3AKR1C2METNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |