Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 5/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KIF5B | P33176 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521668 | 0.83 | EGFR (0.31) | IRAK4TNFRIPK2EGFRRET | |
| SCHEMBL25522053 | 0.78 | TNF (0.31) | TNFEGFR | |
| SCHEMBL25523899 | 0.74 | AKR1C3 (0.42) | KDRAKR1C3AKR1C2 | |
| SCHEMBL25519674 | 0.72 | CAMKK1 (0.36) | IRAK4RIPK2EGFRRETKIF5B | |
| SCHEMBL25522051 | 0.71 | RPS6KA3 (0.42) | AKR1C3AKR1C2 | |
| SCHEMBL25524049 | 0.70 | EGFR (0.36) | EGFR | |
| SCHEMBL24037705 | 0.70 | KDR (0.41) | IRAK4RIPK2EGFRRETKIF5B | |
| SCHEMBL1011251 | 0.69 | IRAK4 (0.39) | IRAK4RIPK2EGFRRETKIF5B | |
| SCHEMBL25521800 | 0.68 | AAK1 (0.47) | — | |
| SCHEMBL25522058 | 0.68 | ADORA2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |