Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523417 | 0.84 | KDM4E (0.42) | KDM4EL3MBTL1MPIPIK3CDCOMT | |
| SCHEMBL25521799 | 0.82 | TOP2A (0.40) | KDM4EL3MBTL1MPIPIK3CDCOMT | |
| SCHEMBL25523901 | 0.82 | ERN1 (0.37) | KDM4ECOMTMAPT | |
| SCHEMBL25521795 | 0.78 | KDM4E (0.48) | KDM4EL3MBTL1COMTNPC1 | |
| SCHEMBL25521916 | 0.75 | ERN1 (0.46) | — | |
| SCHEMBL25523899 | 0.75 | AKR1C3 (0.42) | NPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL25523955 | 0.74 | KDM4E (0.43) | KDM4EL3MBTL1COMTNPC1LMNA | |
| SCHEMBL25523953 | 0.73 | RPS6KA3 (0.33) | KDM4EL3MBTL1MPIPIK3CD | |
| SCHEMBL25522046 | 0.72 | CYP11B1 (0.42) | KDM4E | |
| SCHEMBL25522043 | 0.71 | VRK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |