Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.30 |
| ▸ | FEN1 | P39748 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521799 | 0.79 | TOP2A (0.40) | PIK3CDKDRKDM4EMPIL3MBTL1 | |
| SCHEMBL25522060 | 0.74 | HSP90AA1 (0.34) | HSP90AA1 | |
| SCHEMBL25523903 | 0.73 | KDM4E (0.40) | PIK3CDKDM4EMPIL3MBTL1 | |
| SCHEMBL25520948 | 0.72 | L3MBTL1 (0.38) | RPS6KA3PIK3CDABL1EGFRHCK | |
| SCHEMBL25522051 | 0.71 | RPS6KA3 (0.42) | RPS6KA3AKR1C3AKR1C2KDM4E | |
| SCHEMBL25521800 | 0.71 | AAK1 (0.47) | — | |
| SCHEMBL25524102 | 0.70 | ABCG2 (0.47) | ABL1GCGRKDM4E | |
| SCHEMBL25522043 | 0.70 | VRK1 (0.36) | RPS6KA3 | |
| SCHEMBL25521795 | 0.70 | KDM4E (0.48) | KDM4EL3MBTL1 | |
| SCHEMBL25521794 | 0.70 | KDM4E (0.39) | HSP90AA1ALOX5APFEN1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |