Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523412 | 0.82 | AHR (0.35) | KDM4EMAPK10AKR1C3AKR1C2NPC1 | |
| SCHEMBL25522217 | 0.80 | RPS6KA3 (0.35) | KDM4EHSD17B1HSD17B2 | |
| SCHEMBL25524009 | 0.77 | KDM4E (0.53) | KDM4EHSP90AA1RAB9A | |
| SCHEMBL25521795 | 0.75 | KDM4E (0.48) | KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL25523899 | 0.74 | AKR1C3 (0.42) | AKR1C3AKR1C2NPC1 | |
| SCHEMBL25521799 | 0.74 | TOP2A (0.40) | KDM4EL3MBTL1 | |
| SCHEMBL25522051 | 0.73 | RPS6KA3 (0.42) | KDM4EAKR1C3AKR1C2 | |
| SCHEMBL25521932 | 0.73 | KDM4E (0.49) | KDM4EAKR1C3AKR1C2PARP1HSD17B1 | |
| SCHEMBL25524102 | 0.73 | ABCG2 (0.47) | KDM4EPARP1 | |
| SCHEMBL25519641 | 0.70 | GABRA1 (0.44) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |