Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521410 | 0.83 | RAF1 (0.41) | RAF1BRAFMAPKAPK2PIK3CASLC22A12 | |
| SCHEMBL25523956 | 0.82 | MAPKAPK2 (0.44) | RAF1BRAFTNFMAPKAPK2 | |
| SCHEMBL25524046 | 0.81 | TGFBR1 (0.44) | TNFMAPK10MAPKAPK2PIK3CA | |
| SCHEMBL25522057 | 0.81 | TGFBR1 (0.40) | PIK3CA | |
| SCHEMBL25521800 | 0.80 | AAK1 (0.47) | — | |
| SCHEMBL25524005 | 0.78 | TLR8 (0.41) | PDGFRBPDGFRA | |
| SCHEMBL25522059 | 0.77 | MAP4K4 (0.54) | — | |
| SCHEMBL25524007 | 0.75 | PDGFRB (0.40) | PDGFRBPDGFRAMAPK10CLK4PIK3CA | |
| SCHEMBL25522043 | 0.74 | VRK1 (0.36) | RPS6KA3 | |
| SCHEMBL25523902 | 0.73 | TNIK (0.45) | DYRK1APDGFRBPDGFRACLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |