Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SNCA | P37840 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977454 | 0.89 | MAPT (0.61) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL4607773 | 0.89 | MAPT (0.86) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL6658275 | 0.87 | MAPK13 (0.79) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL9396738 | 0.83 | MAPT (0.91) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL4647245 | 0.83 | MAPT (0.76) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL1636651 | 0.83 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL29388147 | 0.82 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| SCHEMBL217480 | 0.82 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| Methane SCHEMBL28002603 | 0.81 | MAPT (0.96) | MAPTKDM4ESMN1; SMN2ALOX15TP53 | |
| Hydrochloric Acid SCHEMBL29809096 | 0.80 | MAPT (0.95) | MAPTKDM4ESMN1; SMN2ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507189-A | Chemically synthesized bulk drug and application thereof in treating tuberculosis and drug-resistant tuberculosis | 余述南 | 2022-05-17 | — | — | CN | claimed |
| CN-112521339-A | Preparation method of chlorphenazine | 山西立业制药有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-120441496-A | Preparation method of clofazimine key intermediate | 仁合益康集团有限公司 | 2025-08-08 | — | — | CN | disclosed |
| CN-109293587-B | Preparation method of clofazimine and intermediate thereof | 浙江华海立诚药业有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-109293587-B | Preparation method of clofazimine and intermediate thereof | 浙江华海立诚药业有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114507189-A | Chemically synthesized bulk drug and application thereof in treating tuberculosis and drug-resistant tuberculosis | 余述南 | 2022-05-17 | — | — | CN | disclosed |
| CN-114380767-A | Thiazole amide compound containing diphenylamino group and preparation method and application thereof | 安徽理工大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-113454057-A | Intermediate for preparing phenazine derivative and preparation method thereof | ST制药株式会社 | 2021-09-28 | — | — | CN | disclosed |
| US-20210115489-A1 | NOVEL MEDIATOR | KIKKOMAN CORPORATION (JP) | 2021-04-22 | — | — | US | disclosed |
| US-20210115489-A1 | NOVEL MEDIATOR | KIKKOMAN CORPORATION (JP) | 2021-04-22 | — | — | US | disclosed |
| CN-112521339-A | Preparation method of chlorphenazine | 山西立业制药有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-4358579-A | FIBERS, FILMS, LAMINATES, COATINGS | STANDARD OIL COMPANY (INDIANA) (US) | 1982-11-09 | — | — | US | disclosed |
| US-4315854-A | Chromium and cobalt complex amino hydroxy azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4296114-A | 3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof | FISONS LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
| EP-0018939-A1 | 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs | CIBA-GEIGY AG (CH) | 1980-11-12 | — | — | EP | disclosed |
| EP-0008864-A1 | Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them | FISONS plc (GB) | 1980-03-19 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115489-A1 | NOVEL MEDIATOR | MPO, EPX, LPO | MAPT 4015/4885KDM4E 2284/4885SMN1; SMN2 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.