Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523405 | 1.00 | RAB9A (0.48) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25522603 | 0.88 | POLB (0.47) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25525421 | 0.85 | RAB9A (0.49) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25518860 | 0.83 | SMN1; SMN2 (0.53) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25520028 | 0.80 | RAB9A (0.44) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25525471 | 0.78 | MAPT (0.49) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25522666 | 0.78 | MAPT (0.49) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23522306 | 0.77 | ALDH1A1 (0.51) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL10639437 | 0.77 | RAB9A (0.50) | RAB9AALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL25522587 | 0.76 | RAB9A (0.53) | RAB9AALDH1A1GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | RAB9A 2211/4885ALDH1A1 2269/4885GAA 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.