SCHEMBL25524938

SCHEMBL25524938

CCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.44
▸ NMUR2 Q9GZQ4 5/20 0.43
▸ NMUR1 Q9HB89 5/20 0.43
▸ F2 P00734 4/20 0.42
▸ RAMP3 O60896 8/20 0.41
▸ CALCR P30988 8/20 0.41
▸ NPY1R P25929 1/20 0.40
▸ NPY2R P49146 1/20 0.40
▸ NPY4R P50391 1/20 0.40
▸ NPY5R Q15761 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25524928 0.99 APLNR (0.45) APLNRNMUR2NMUR1F2RAMP3
SCHEMBL25524962 0.98 NMUR2 (0.46) APLNRNMUR2NMUR1F2RAMP3
SCHEMBL22019477 0.96 NPY2R (0.44) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL25524960 0.96 RAMP3 (0.46) RAMP3CALCRNPY1RNPY2RNPY4R
SCHEMBL25524949 0.96 F2 (0.45) F2CALCRNPY1RNPY2RNPY4R
SCHEMBL22018604 0.95 APLNR (0.45) APLNRRAMP3CALCRNPY1RNPY2R
SCHEMBL25524970 0.95 APLNR (0.44) APLNRNMUR2NMUR1F2RAMP3
SCHEMBL22018361 0.95 APLNR (0.46) APLNRF2RAMP3CALCRNPY1R
SCHEMBL22018477 0.95 APLNR (0.46) APLNRRAMP3CALCRNPY1RNPY2R
SCHEMBL22922932 0.95 APLNR (0.46) APLNRRAMP3CALCRNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885NMUR2 1237/4885NMUR1 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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