SCHEMBL25524960

SCHEMBL25524960

CCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(C)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 11/20 0.46
▸ CALCR P30988 11/20 0.46
▸ NPY2R P49146 6/20 0.44
▸ NPY4R P50391 6/20 0.44
▸ NPY5R Q15761 6/20 0.44
▸ NPY1R P25929 4/20 0.44
▸ MAPK8 P45983 1/20 0.43
▸ MAPK9 P45984 1/20 0.43
▸ MAPK10 P53779 1/20 0.43
▸ KEAP1 Q14145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25524938 0.96 APLNR (0.44) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL22922809 0.96 NPY2R (0.46) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL22019477 0.96 NPY2R (0.44) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL22019191 0.96 NPY2R (0.46) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL25524928 0.96 APLNR (0.45) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL25524949 0.95 F2 (0.45) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL25524962 0.94 NMUR2 (0.46) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL22018329 0.92 NPY2R (0.47) NPY2RNPY4RNPY5RNPY1R
SCHEMBL22018604 0.92 APLNR (0.45) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL22018328 0.92 NPY2R (0.47) CALCRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP RAMP3 1263/4885CALCR 72/4885NPY2R 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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