SCHEMBL25524970

SCHEMBL25524970

CCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(=O)NC)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.44
▸ NMUR2 Q9GZQ4 6/20 0.43
▸ NMUR1 Q9HB89 6/20 0.43
▸ RAMP3 O60896 8/20 0.40
▸ CALCR P30988 8/20 0.40
▸ NMBR P28336 1/20 0.39
▸ GRPR P30550 1/20 0.39
▸ F2 P00734 1/20 0.39
▸ MAPK8 P45983 1/20 0.39
▸ MAPK9 P45984 1/20 0.39
▸ MAPK10 P53779 1/20 0.39
▸ NAA50 Q9GZZ1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018359 0.96 APLNR (0.45) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL25524938 0.95 APLNR (0.44) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL25524928 0.94 APLNR (0.45) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL25524958 0.94 APLNR (0.43) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL22019192 0.94 APLNR (0.45) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL25524962 0.93 NMUR2 (0.46) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL22018529 0.92 NAA50 (0.44) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL22018369 0.92 APLNR (0.46) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL22018380 0.91 APLNR (0.48) APLNRNMUR2NMUR1RAMP3CALCR
SCHEMBL22018363 0.91 APLNR (0.48) APLNRNMUR2NMUR1RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885NMUR2 1237/4885NMUR1 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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