Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255251 | 0.94 | GAA (0.76) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL11652211 | 0.88 | KMT2A (0.67) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL17865783 | 0.85 | MLYCD (0.73) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL18082335 | 0.84 | NPC1 (0.71) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL14197819 | 0.83 | GPR139 (0.68) | KMT2AGAAHSD17B10NPC1RAB9A | |
| SCHEMBL27386734 | 0.81 | NPC1 (0.61) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL3377096 | 0.81 | NPC1 (0.66) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL8507006 | 0.81 | NPC1 (0.66) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL8506869 | 0.81 | NPC1 (0.66) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL16105693 | 0.81 | KMT2A (0.67) | KMT2AGAAHSD17B10SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020404-A1 | Cyanomethyl substituted N-Acyl Tryptamines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |