Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300123 | 1.00 | CYP2C19 (0.49) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7306770 | 0.90 | CYP2C19 (0.46) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2553408 | 0.90 | CYP2C19 (0.46) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7303931 | 0.83 | CYP2D6 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5682810 | 0.82 | ANPEP (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1168400 | 0.81 | EPHX1 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6EPHX1 | |
| SCHEMBL2549520 | 0.81 | EPHX1 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6EPHX1 | |
| SCHEMBL7114970 | 0.81 | EPHX1 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6EPHX1 | |
| SCHEMBL7347761 | 0.81 | CYP2C19 (0.57) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL11535678 | 0.81 | CYP2C19 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845299-B2 | Process for the preparation of a fluorolacton derivative | GILEAD PHARMASSET LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20170183317-A1 | PROCESS FOR THE PREPARATION OF A FLUOROLACTION DERIVATIVE | GILEAD SCIENCES, INC. | 2017-06-29 | — | — | US | disclosed |
| EP-2556052-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | Sumitomo Chemical Company, Limited (JP) | 2013-02-13 | — | — | EP | disclosed |
| EP-2556051-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | Sumitomo Chemical Company, Limited (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-20130035506-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20130023696-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| CN-102834376-A | Process for producing sulfur-containing amino acids | SUMITOMO CHEMICAL CORP | 2012-12-19 | — | — | CN | disclosed |
| CN-102822146-A | Process for producing sulfur-containing amino acids | SUMITOMO CHEMICAL CO | 2012-12-12 | — | — | CN | disclosed |
| WO-2011126130-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011126129-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035506-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | AADAT, BCAT2, CBS | CYP2C19 2894/4885CYP1A2 882/4885CYP3A4 1202/4885 |
| US-20130023696-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | CBS, CTH, BCAT2 | CYP2C19 2967/4885CYP1A2 664/4885CYP3A4 1287/4885 |
| US-20170183317-A1 | PROCESS FOR THE PREPARATION OF A FLUOROLACTION DERIVATIVE | CYP3A5, CYP2F1, CYP7A1 | CYP2C19 57/4885CYP1A2 47/4885CYP3A4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.