Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 4/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19439103 | 0.84 | HPGD (0.77) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30052001 | 0.78 | HPGD (0.43) | HPGDSLC6A2SLC6A4SLC6A3CFD | |
| SCHEMBL23885459 | 0.78 | HPGD (0.43) | HPGDSLC6A2SLC6A4SLC6A3CFD | |
| SCHEMBL23885461 | 0.78 | HPGD (0.43) | HPGDSLC6A2SLC6A4SLC6A3CFD | |
| SCHEMBL1464415 | 0.76 | HPGD (0.58) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23885409 | 0.74 | PDF (0.43) | HPGDCFDKIF18AGRM5 | |
| SCHEMBL29902300 | 0.72 | HPGD (0.53) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18591276 | 0.72 | HPGD (0.53) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23885542 | 0.72 | HPGD (0.42) | HPGDSLC6A2SLC6A4SLC6A3CFD | |
| SCHEMBL23885545 | 0.72 | HPGD (0.42) | HPGDSLC6A2SLC6A4SLC6A3CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | HPGD 808/4885SMN1; SMN2 1298/4885SLC6A2 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.