SCHEMBL25527382

SCHEMBL25527382

O=C(CS)Oc1ccc(I)cc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.43
PTPRC P08575 1/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPRA P18433 1/20 0.41
PTPRB P23467 1/20 0.41
PTPRE P23469 1/20 0.41
PTPN6 P29350 1/20 0.41
FOLH1 Q04609 4/20 0.39
KDM4E B2RXH2 5/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 4/20 0.37
HPGD P15428 3/20 0.37
MAPT P10636 1/20 0.37
PTGS1 P23219 2/20 0.35
PTGS2 P35354 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25528393 0.90 CFD (0.38) CFDPTPRCPTPN2PTPN1PTPRA
SCHEMBL25527338 0.88 KDM4E (0.42) CFDPTPRCPTPN2PTPN1PTPRA
SCHEMBL25527383 0.87 KDM4E (0.41) CFDPTPRCPTPN2PTPN1PTPRA
SCHEMBL25529018 0.81 CFD (0.31) CFD
SCHEMBL25527368 0.81 KEAP1 (0.46) CFDFOLH1KDM4EMEN1RECQL
SCHEMBL1319089 0.78 CFD (0.69) CFDPTPRCPTPN2PTPN1PTPRA
SCHEMBL11092078 0.76 KDM4E (0.61) FOLH1KDM4EMEN1RECQLKMT2A
SCHEMBL3296817 0.75 PTPRC (0.47) CFDPTPRCPTPN2PTPN1PTPRA
SCHEMBL25527371 0.74 TSHR (0.44) FOLH1KDM4EALDH1A1TSHRGAA
SCHEMBL25527385 0.74 MAOB (0.39) PTPRCPTPN2PTPN1PTPRAPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152696-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed