SCHEMBL2552768

SCHEMBL2552768

O=C(/C=C/c1ccccc1)Oc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
KMT2A Q03164 10/20 0.50
LMNA P02545 4/20 0.50
MEN1 O00255 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 3/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552437 0.84 RAB9A (0.46) ESR1ESR2KMT2AMEN1L3MBTL1
SCHEMBL1331344 0.81 RAB9A (0.44) KMT2AMEN1L3MBTL1NPSR1ALDH1A1
SCHEMBL30616301 0.80 RAB9A (0.49) KMT2AMEN1NPSR1ALDH1A1MAOA
SCHEMBL28462915 0.79 LMNA (0.53) KMT2ALMNAMEN1MAOBMAPT
SCHEMBL8840922 0.78 RAB9A (0.54) KMT2AMEN1NPSR1ALDH1A1MAOA
Phenol SCHEMBL25403614 0.78 RAB9A (0.40) ESR1ESR2KMT2AMEN1ALDH1A1
SCHEMBL30695173 0.77 RAB9A (0.47) KMT2AMEN1NPSR1ALDH1A1MAOA
SCHEMBL27971781 0.77 RAB9A (0.45) ESR1ESR2KMT2AMEN1L3MBTL1
SCHEMBL20917777 0.77 RAB9A (0.49) KMT2AMEN1NPSR1ALDH1A1MAOA
SCHEMBL28608606 0.77 MAPT (0.53) KMT2ALMNAMEN1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130090031-A1 COMPOSITE FILM MATERIAL COMPRISING A RESIN OF FLUORENE CROTONATE, FLUORENE CINNAMATE, FLUORENE ACRYLATE, FLUORENE METHACRYLATE, FLUORENE ALLYLETHER OR A COMBINATION THEREOF FERRANIA TECHNOLOGIES S.P.A. (IT) 2013-04-11 US disclosed
EP-2556113-A1 COMPOSITE FILM MATERIAL COMPRISING A RESIN OF FLUORENE CROTONATE, FLUORENE CINNAMATE, FLUORENE ACRYLATE, FLUORENE METHACRYLATE, FLUORENE ALLYLETHER OR A COMBINATION THEREOF Ferrania Technologies S.p.A. (IT) 2013-02-13 EP disclosed
EP-2556113-A1 COMPOSITE FILM MATERIAL COMPRISING A RESIN OF FLUORENE CROTONATE, FLUORENE CINNAMATE, FLUORENE ACRYLATE, FLUORENE METHACRYLATE, FLUORENE ALLYLETHER OR A COMBINATION THEREOF Ferrania Technologies S.p.A. (IT) 2013-02-13 EP disclosed
WO-2011124522-A1 COMPOSITE FILM MATERIAL COMPRISING A RESIN OF FLUORENE CROTONATE, FLUORENE CINNAMATE, FLUORENE ACRYLATE, FLUORENE METHACRYLATE, FLUORENE ALLYLETHER OR A COMBINATION THEREOF FERRANIA TECHNOLOGIES S.P.A. (IT) 2011-10-13 WO disclosed
WO-2011124522-A1 COMPOSITE FILM MATERIAL COMPRISING A RESIN OF FLUORENE CROTONATE, FLUORENE CINNAMATE, FLUORENE ACRYLATE, FLUORENE METHACRYLATE, FLUORENE ALLYLETHER OR A COMBINATION THEREOF FERRANIA TECHNOLOGIES S.P.A. (IT) 2011-10-13 WO disclosed
EP-1819648-B1 PHOTOREACTIVE COMPOUND, LIQUID CRYSTAL ALIGNMENT LAYER USING THE COMPOUND, METHOD OF MANUFACTURING THE ALIGNMENT LAYER, AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE ALIGNMENT LAYER LG CHEMICAL LTD (KR) 2009-04-15 EP disclosed
US-7422778-B2 Photoreactive compound, liquid crystal alignment layer using the compound, method of manufacturing the alignment layer, and liquid crystal display device containing the alignment layer LG CHEM, LTD. (KR) 2008-09-09 US disclosed
EP-1819648-A4 PHOTOREACTIVE COMPOUND, LIQUID CRYSTAL ALIGNMENT LAYER USING THE COMPOUND, METHOD OF MANUFACTURING THE ALIGNMENT LAYER, AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE ALIGNMENT LAYER LG CHEMICAL LTD (KR) 2008-02-13 EP disclosed
EP-1819648-A1 PHOTOREACTIVE COMPOUND, LIQUID CRYSTAL ALIGNMENT LAYER USING THE COMPOUND, METHOD OF MANUFACTURING THE ALIGNMENT LAYER, AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE ALIGNMENT LAYER LG Chemical Ltd. (KR) 2007-08-22 EP disclosed
US-20060121213-A1 Photoreactive compound, liquid crystal alignment layer using the compound, method of manufacturing the alignment layer, and liquid crystal display device containing the alignment layer LG CHEM, LTD. (KR) 2006-06-08 US disclosed
WO-2006059884-A1 PHOTOREACTIVE COMPOUND, LIQUID CRYSTAL ALIGNMENT LAYER USING THE COMPOUND, METHOD OF MANUFACTURING THE ALIGNMENT LAYER, AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE ALIGNMENT LAYER LG CHEM, LTD. (KR) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060121213-A1 Photoreactive compound, liquid crystal alignment layer using the compound, method of manufacturing the alignment layer, and liquid crystal display device containing the alignment layer CRY1, C9, CXCR1 ESR1 2690/4885ESR2 4729/4885KMT2A 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.