Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733122 | 0.86 | GAA (0.47) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL3727253 | 0.83 | LGMN (0.45) | GAAMEN1KMT2AADRA2CMAPT | |
| SCHEMBL30923161 | 0.82 | KEAP1 (0.59) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL3433100 | 0.81 | ADRA2C (0.64) | GAAKMT2AADRA2CHTR3ADRD2 | |
| SCHEMBL30393203 | 0.80 | GAA (0.42) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL23379453 | 0.79 | GAA (0.72) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL30108629 | 0.79 | GAA (0.72) | GAAMEN1USP2KMT2AADRA2C | |
| Hydrochloric Acid SCHEMBL6354856 | 0.79 | ADRA2C (0.62) | GAAKMT2AADRA2CHTR3ADRD2 | |
| SCHEMBL24130679 | 0.77 | JAK2 (0.45) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL17265362 | 0.74 | GAA (0.40) | GAAMEN1USP2KMT2AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |