Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27293546 | 0.83 | KEAP1 (0.59) | LMNASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL30923161 | 0.83 | KEAP1 (0.59) | LMNASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL25527740 | 0.83 | GAA (0.53) | LMNAALDH1A1GAAMAPTMEN1 | |
| SCHEMBL3433100 | 0.82 | ADRA2C (0.64) | LMNAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL25528036 | 0.81 | PDCD1LG2 (0.35) | LMNASMN1; SMN2ALDH1A1P2RX7TSHR | |
| Hydrochloric Acid SCHEMBL6354856 | 0.81 | ADRA2C (0.62) | LMNAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL4435301 | 0.80 | LGMN (0.50) | LGMNLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL26099996 | 0.79 | GAA (0.42) | LMNASMN1; SMN2ALDH1A1P2RX7GAA | |
| SCHEMBL30393203 | 0.79 | GAA (0.42) | LMNASMN1; SMN2ALDH1A1P2RX7GAA | |
| SCHEMBL13075047 | 0.78 | PRKDC (0.41) | LMNASMN1; SMN2ALDH1A1P2RX7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2010125103-A1 | DIKETOPIPERAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |