Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085939 | 0.95 | MEN1 (0.57) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL9153749 | 0.94 | LMNA (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL28214715 | 0.94 | LMNA (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL5722029 | 0.94 | LMNA (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL2552794 | 0.92 | KMT2A (0.51) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL28423316 | 0.90 | CA12 (0.55) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL8820845 | 0.86 | MEN1 (0.48) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL124096 | 0.85 | LMNA (0.55) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL29994009 | 0.85 | KMT2A (0.69) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL301123 | 0.85 | KMT2A (0.69) | KMT2AMEN1KDM4ERECQLNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040013734-A1 | Mixture of water insoluble drug and polymer | PFIZER INC. | 2004-01-22 | — | — | US | claimed |
| EP-1027886-A2 | Pharmaceutical solid dispersions | Pfizer Products Inc. (US) | 2000-08-16 | — | — | EP | claimed |
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
| EP-0645023-A1 | IMAGEABLE ARTICLES HAVING DYE SELECTIVE INTERLAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025936-A2 | IMAGEABLE ARTICLES HAVING DYE SELECTIVE INTERLAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040013734-A1 | Mixture of water insoluble drug and polymer | ABCG2, ABCB1, ABCB11 | KMT2A 3238/4885MEN1 4410/4885KDM4E 2176/4885 |
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | TAS2R20, BLVRB, FDPS | KMT2A 4018/4885MEN1 2747/4885KDM4E 385/4885 |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | TAS2R20, BLVRB, NOTUM | KMT2A 4257/4885MEN1 2980/4885KDM4E 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.