Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528885 | 0.88 | ADORA2A (0.44) | TGFBR1TGFBR2 | |
| SCHEMBL25528897 | 0.86 | TGFBR1 (0.60) | TGFBR1TGFBR2 | |
| SCHEMBL25528895 | 0.86 | TGFBR1 (0.54) | TGFBR1TGFBR2 | |
| SCHEMBL25211299 | 0.78 | TGFBR1 (0.42) | TGFBR1TGFBR2 | |
| SCHEMBL25528877 | 0.75 | ADORA2A (0.45) | — | |
| SCHEMBL25528249 | 0.74 | ADORA2A (0.52) | — | |
| SCHEMBL22125562 | 0.71 | TGFBR1 (0.45) | TGFBR1TGFBR2 | |
| SCHEMBL25528890 | 0.69 | MAPK14 (0.47) | — | |
| SCHEMBL25528952 | 0.69 | ADORA2A (0.55) | TGFBR1 | |
| SCHEMBL25528882 | 0.69 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |