Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116437 | 0.84 | LMNA (0.57) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL23003768 | 0.81 | LMNA (0.54) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL23003828 | 0.81 | LMNA (0.54) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL9270669 | 0.81 | LMNA (0.49) | LMNAALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL1250518 | 0.80 | LMNA (0.53) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL3927973 | 0.80 | GAA (0.53) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL13116440 | 0.79 | LMNA (0.46) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL30087171 | 0.79 | LMNA (0.60) | LMNAALDH1A1KDM4EPTGS2KMT2A | |
| SCHEMBL7433745 | 0.79 | LMNA (0.59) | LMNAALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL7044593 | 0.77 | PTGS2 (0.54) | LMNAALDH1A1KDM4EPTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | LMNA 1391/4885ALDH1A1 1020/4885KDM4E 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.