SCHEMBL7433745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6815943	0.86	LMNA (0.56)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL21999631	0.85	ACLY (0.55)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL7334329	0.84	LMNA (0.54)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL15517469	0.84	LMNA (0.53)	LMNAKDM4EKMT2APTGS2MAPT
	SCHEMBL10981786	0.83	CYP1A2 (0.45)	LMNAKDM4EKMT2AMAPTALDH1A1
	SCHEMBL5109846	0.81	KMT2A (0.65)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL3349589	0.81	ALDH1A1 (0.46)	LMNAKDM4EKMT2AMAPTALDH1A1
	SCHEMBL6812567	0.80	LMNA (0.50)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL7329205	0.80	LMNA (0.50)	LMNAKDM4EKMT2AACLYPTGS2
	SCHEMBL25528281	0.79	LMNA (0.56)	LMNAKDM4EKMT2APTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.