SCHEMBL25528337 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	BRD4	O60885	2/20	0.39

▸	ROCK2	O75116	6/20	0.36

▸	ROCK1	Q13464	4/20	0.36

▸	CACNA1G	O43497	5/20	0.36

▸	ALDH1A1	P00352	2/20	0.36

▸	GAA	P10253	1/20	0.35

▸	THRB	P10828	1/20	0.35

▸	DPP4	P27487	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25528339	0.88	PARP1 (0.41)	BRD4ROCK2ROCK1CACNA1GTHRB
SCHEMBL25528328	0.78	BRD4 (0.43)	BRD4ROCK2ROCK1DPP4
SCHEMBL25528351	0.77	BRD4 (0.34)	BRD4CACNA1GALDH1A1GAATHRB
SCHEMBL25529692	0.77	ROCK2 (0.52)	ROCK2ROCK1
SCHEMBL25528758	0.76	PARP1 (0.42)	BRD4ROCK2CACNA1GTHRB
SCHEMBL25528752	0.74	PARP1 (0.42)	BRD4ROCK2ROCK1CACNA1GTHRB
SCHEMBL25529498	0.70	MAPT (0.48)	ROCK2ROCK1GAATHRB
SCHEMBL25529068	0.70	ROCK2 (0.43)	ROCK2ROCK1
SCHEMBL25529501	0.69	ROCK1 (0.47)	BRD4ROCK2ROCK1
SCHEMBL25529500	0.69	ROCK2 (0.59)	BRD4ROCK2ROCK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023093787-A1	BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR	成都奥睿药业有限公司	2023-06-01	—	—	WO	disclosed