SCHEMBL25528612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25528683	0.94	THRB (0.47)	THRATHRBHSP90AA1HSP90B1MAOB
	SCHEMBL25528702	0.91	THRA (0.53)	THRATHRBHSP90AA1HSP90B1MAOB
	SCHEMBL25528657	0.91	THRA (0.55)	THRATHRBHSP90AA1MAOBMAOA
	SCHEMBL25528655	0.90	THRA (0.50)	THRATHRBMAOBMAOAALDH1A1
	SCHEMBL23003632	0.90	THRB (0.62)	THRATHRBHSP90AA1HSP90B1MEN1
	SCHEMBL25528658	0.90	THRB (0.54)	THRATHRBHSP90AA1MAOBMEN1
	SCHEMBL25528726	0.90	THRA (0.56)	THRATHRBHSP90AA1MEN1KMT2A
	SCHEMBL25528656	0.89	THRA (0.49)	THRATHRBMAOBMAOAMEN1
	SCHEMBL23003765	0.89	THRA (0.51)	THRATHRBHSP90AA1HSP90B1MEN1
	SCHEMBL23003773	0.89	THRA (0.51)	THRATHRBHSP90AA1HSP90B1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.