Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.54 |
| ▸ | THRA | P10827 | 10/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528657 | 0.92 | THRA (0.55) | THRBTHRASLC7A5MAOBHSP90AA1 | |
| SCHEMBL23003803 | 0.91 | THRB (0.65) | THRBTHRA | |
| SCHEMBL25528726 | 0.91 | THRA (0.56) | THRBTHRASLC7A5HSP90AA1MEN1 | |
| SCHEMBL25528612 | 0.90 | THRA (0.53) | THRBTHRASLC7A5MAOBHSP90AA1 | |
| SCHEMBL23003668 | 0.89 | THRA (0.52) | THRBTHRACYP3A4 | |
| SCHEMBL25528646 | 0.89 | THRA (0.52) | THRBTHRASLC7A5CYP3A4 | |
| SCHEMBL25528638 | 0.87 | THRA (0.50) | THRBTHRASLC7A5HSP90AA1 | |
| SCHEMBL25528664 | 0.87 | THRB (0.50) | THRBTHRASLC7A5MEN1CYP3A4 | |
| SCHEMBL25528683 | 0.86 | THRB (0.47) | THRBTHRAMAOBHSP90AA1 | |
| SCHEMBL25528661 | 0.86 | THRB (0.51) | THRBTHRASLC7A5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | THRB 9/4885THRA 4/4885SLC7A5 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.