Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528467 | 0.91 | HTR7 (0.34) | HTR7 | |
| SCHEMBL25528469 | 0.87 | POLB (0.36) | POLBCACNA1GBRD4THRBROCK2 | |
| SCHEMBL25528346 | 0.86 | ROCK2 (0.36) | CACNA1GBRD4THRBROCK2ROCK1 | |
| SCHEMBL25528831 | 0.81 | HTR7 (0.36) | HTR7BRD4ROCK2ROCK1 | |
| SCHEMBL25528466 | 0.80 | ROCK2 (0.37) | CACNA1GBRD4THRBROCK2ROCK1 | |
| SCHEMBL25529880 | 0.79 | HTR7 (0.33) | HTR7 | |
| SCHEMBL25528343 | 0.79 | PARP1 (0.43) | BRD4ROCK2ROCK1 | |
| SCHEMBL25528465 | 0.78 | CACNA1H (0.33) | BRD4 | |
| SCHEMBL25528830 | 0.78 | HPGD (0.33) | — | |
| SCHEMBL25528478 | 0.76 | ROCK2 (0.41) | CACNA1GBRD4THRBROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |