Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.32 |
| ▸ | GSAP | A4D1B5 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528469 | 0.90 | POLB (0.36) | HPGD | |
| SCHEMBL25528467 | 0.87 | HTR7 (0.34) | — | |
| SCHEMBL25528468 | 0.87 | CACNA1H (0.36) | WDR5 | |
| SCHEMBL25529880 | 0.86 | HTR7 (0.33) | — | |
| SCHEMBL25528762 | 0.84 | CACNA1H (0.34) | — | |
| SCHEMBL25528465 | 0.80 | CACNA1H (0.33) | — | |
| SCHEMBL25528834 | 0.78 | HTR7 (0.33) | — | |
| SCHEMBL25528466 | 0.77 | ROCK2 (0.37) | — | |
| SCHEMBL25528343 | 0.76 | PARP1 (0.43) | — | |
| SCHEMBL25528831 | 0.75 | HTR7 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |