Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886857 | 0.80 | — | — | |
| SCHEMBL269050 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TDP1KMT2A | |
| SCHEMBL14321595 | 0.77 | CYP2D6 (0.34) | ALDH1A1TDP1KMT2A | |
| SCHEMBL14035478 | 0.76 | MAPK1 (0.35) | ALDH1A1TDP1KMT2A | |
| SCHEMBL20711453 | 0.76 | SLC22A6 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL13543295 | 0.76 | MAPK1 (0.35) | ALDH1A1TDP1KMT2A | |
| SCHEMBL23913764 | 0.76 | SLC22A6 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL14346986 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1 | |
| SCHEMBL18561859 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1 | |
| SCHEMBL6563687 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-11655239-B2 | Fused ring pyrimidine amino compound and preparation method, pharmaceutical composition, and use thereof | Shanghai Institute of Material Medica, Chinese Academy of Sciences (CN) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | ALDH1A1 3752/4885TDP1 4219/4885KMT2A 4067/4885 |
| US-11655239-B2 | Fused ring pyrimidine amino compound and preparation method, pharmaceutical composition, and use thereof | DDR2, DDR1, DOCK2 | ALDH1A1 3898/4885TDP1 381/4885KMT2A 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.