Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530558 | 0.86 | CYP1A2 (0.37) | CYP1A2CYP2C19CYP2D6SLC6A4SLC6A2 | |
| SCHEMBL25530571 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP2D6SLC6A4SLC6A2 | |
| SCHEMBL25530554 | 0.81 | SLC6A4 (0.39) | ADRA2ACYP1A2CYP2C19CYP2D6SLC6A4 | |
| SCHEMBL25530551 | 0.80 | ADRA2A (0.42) | ADRA2ACYP1A2CYP2C19CYP2D6SLC6A4 | |
| SCHEMBL25574716 | 0.72 | CA1 (0.40) | CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL25530557 | 0.71 | HDAC8 (0.40) | ADRA2ACYP1A2CYP2C19CYP2D6SLC6A4 | |
| SCHEMBL25536709 | 0.71 | CYP1A2 (0.37) | CYP1A2CYP2C19CYP2D6SLC6A4SLC6A2 | |
| SCHEMBL25530562 | 0.68 | HDAC8 (0.33) | ADRA2ACYP2D6HDAC8HTR2AKCNH2 | |
| SCHEMBL25530577 | 0.68 | CYP1A2 (0.41) | CYP1A2CYP2C19CYP2D6CETP | |
| SCHEMBL25530569 | 0.68 | HTR2A (0.37) | ADRA2ACYP1A2CYP2C19SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | ADRA2A 4644/4885MCHR1 4720/4885CYP1A2 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.