Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044658 | 0.90 | GAA (0.52) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL3638211 | 0.82 | NOS2 (0.49) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL3638210 | 0.82 | GPR119 (0.47) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2555289 | 0.80 | KCNA5 (0.60) | MEN1KMT2ASMN1; SMN2GAAKCNA5 | |
| SCHEMBL2550556 | 0.79 | LMNA (0.68) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL30275051 | 0.79 | KCNA5 (0.58) | MEN1KMT2ASMN1; SMN2GAAKCNA5 | |
| Hydrochloric Acid SCHEMBL2547992 | 0.79 | LMNA (0.61) | MEN1KMT2ASMN1; SMN2GAAKCNA5 | |
| SCHEMBL2870098 | 0.77 | LMNA (0.71) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL1162993 | 0.76 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2GAAKCNA5 | |
| SCHEMBL14862646 | 0.76 | KDM4E (0.57) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |