SCHEMBL3638211

SCHEMBL3638211

CCOC(=O)C(c1ccccn1)N1CCN(C(=O)OCC(C)C)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.49
ALDH1A1 P00352 8/20 0.48
KDM4E B2RXH2 3/20 0.48
GAA P10253 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 2/20 0.44
GRM5 P41594 1/20 0.43
LMNA P02545 3/20 0.42
PKM P14618 1/20 0.42
FAAH O00519 1/20 0.42
MGLL Q99685 1/20 0.42
HPGD P15428 2/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3638210 0.85 GPR119 (0.47) NOS2ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL13044658 0.83 GAA (0.52) NOS2ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL2553058 0.82 MEN1 (0.54) NOS2ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL13115589 0.71 DGAT1 (0.49) ALDH1A1KDM4EGAASMN1; SMN2MEN1
SCHEMBL13044640 0.70 GPR119 (0.51) POLBTSHRGRM5ALOX15
SCHEMBL2184519 0.70 SMN1; SMN2 (0.64) ALDH1A1KDM4EGAASMN1; SMN2MEN1
SCHEMBL9289622 0.70 KDM4E (0.64) NOS2ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL2793960 0.69 GPR119 (0.43) NOS2ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL1240900 0.69 ALDH1A1 (0.74) NOS2ALDH1A1KDM4ESMN1; SMN2MEN1
SCHEMBL1583149 0.69 DPP4 (0.49) NOS2ALDH1A1KDM4EKMT2ACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167466-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR Glaxo Group Limited (GB) 2010-03-31 EP disclosed
WO-2008148853-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GLAXO GROUP LIMITED (GB) 2008-12-11 WO disclosed