Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25533321 | 1.00 | SIGMAR1 (0.46) | SIGMAR1SLC6A4ADRA2CADRA1ALMNA | |
| SCHEMBL25446385 | 0.85 | SIGMAR1 (0.46) | SIGMAR1SLC6A4ADRA2CADRA1ALMNA | |
| SCHEMBL25533203 | 0.80 | TAAR1 (0.40) | SLC6A4ADRA2CADRA1AADRB2ADRB3 | |
| SCHEMBL25533342 | 0.80 | TAAR1 (0.40) | SLC6A4ADRA2CADRA1AADRB2ADRB3 | |
| SCHEMBL25533535 | 0.79 | ACACB (0.49) | — | |
| SCHEMBL25533181 | 0.79 | TAAR1 (0.40) | SLC6A4ADRA2CADRA1AADRB2ADRB3 | |
| SCHEMBL25533326 | 0.79 | TAAR1 (0.40) | SLC6A4ADRA2CADRA1AADRB2ADRB3 | |
| SCHEMBL25533453 | 0.78 | ALOX15 (0.49) | SLC6A4ADRA2CADRA1AADRB2ADRB3 | |
| SCHEMBL26060350 | 0.78 | TAAR1 (0.57) | SLC6A4HTR2AHTR2BSLC6A2SLC6A3 | |
| SCHEMBL25533494 | 0.78 | TAAR1 (0.57) | SLC6A4HTR2AHTR2BSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150966-A1 | ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF | TERRAN BIOSCIENCES INC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150966-A1 | ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF | SLC6A3, DBH, PNMT | SIGMAR1 139/4885SLC6A4 12/4885ADRA2C 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.